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Biotechnology Jobs & Careers Search

Find your next job in Biotechnology. Search Biotechnology jobs from thousands of job and career search sites. A search engine for jobs with a different approach to job and career searches. In one simple search, job seekers get free access to millions of employment opportunities from thousands of websites. Find your next job in Biotechnology today.

Health Care a Sound Investment Despite Slow Economy and Reform

Health care investing is making a comeback in 2011. The industry has shaken off irrational fears about reform and refocused on the opportunities that an aging population provides. Compared to industries more closely tied to the economy, it isn't scary at all anymore

Coffee Consumption Reduces Fibrosis Risk in Those With Fatty Liver Disease, Study
Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces the risk of advanced fibrosis in those with nonalcoholic fatty liver disease (NAFLD). Findings published in the February issue of Hepatology, a journal of the American Association...

Merck KGaA Signs $550 Million Cancer Pact With Threshold Pharmaceuticals, Inc.
DARMSTADT, Germany, Feb 03, 2012 (BUSINESS WIRE) -- --Deal provides Threshold with an upfront payment of EUR 19 million ($25 million), plus further potential milestones and royalties as well as an option to co-commercialize in the United States

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, today announced that a global agreement was signed with Threshold Pharmaceuticals, Inc...

Why Red Wine Can Be Healthy: Probable Mechanism Underlying Resveratrol Activity Uncovered, National Institutes of Health (NIH) Study
National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging. Rather, the authors found that resveratrol inhibits certain types of proteins known...

FDA OKs Merck & Co., Inc.'s Janumet XR for Type 2 Diabetes
WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)-- Merck (NYSE:MRK - News), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) approved JANUMET XR (sitagliptin and metformin hydrochloride (HCl) extended-release) tablets, a new treatment for type 2 diabetes that combines sitagliptin, which is the active component of JANUVIA (sitagliptin), with...

Same Genes Linked to Early and Late-Onset Alzheimer's, Washington University Study
The same gene mutations linked to inherited, early-onset Alzheimer's disease have been found in people with the more common late-onset form of the illness.

Gilead Sciences, Inc. Soars on Positive Data From Experimental Hepatitis C Drug; Stock Rises +4.77(9.68%) @ 1:09PM EST
Gilead Sciences Inc. (GILD), the drugmaker that acquired Pharmasset Inc. last month for its experimental hepatitis C treatments, gained in extended trading after saying one of the therapies produced positive clinical trial results. Patients with genotype 1 hepatitis C -- the most common in North America -- had no detectable signs of the virus after four weeks on the drug, PSI-7977, Norbert Bischofberger...

Idenix Pharmaceuticals, Inc. Receives FDA Notification That Partial Clinical Hold on IDX184 Removed
CAMBRIDGE, Mass., Feb. 3, 2012 /PRNewswire/ -- Idenix Pharmaceuticals, Inc. (NASDAQ: IDIX), a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today announced that it has received notification from the U.S. Food and Drug Administration (FDA) that the partial clinical hold on IDX184 has been removed...

Q&A About $100 Million Asia, Emerging Markets Strategy With AstraZeneca PLC's Head of R&D
The health challenges of China and Asia offer big opportunities for multinational pharma companies. Cases of chronic diseases, such as diabetes, are on the rise in the region, as are lung, gastric, and liver cancers. China alone is likely to be the worlds third-largest pharmaceutical market by this year, with sales of more than $50 billion. AstraZeneca, the largest multinational pharmaceutical company...

Elevated Glucose Associated With Undetected Heart Damage, Johns Hopkins University Study
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that hyperglycemia (high blood sugar) injures the heart, even in patients without a history of heart disease or diabetes. Researchers found that elevated levels of glycated hemoglobin (HbA1c), a marker for chronic hyperglycemia and diabetes, were associated with minute levels of the protein troponin T (cTnT...

New Technique Successfully Dissolves Blood Clots in Brain and Lowers Risk of Brain Damage After Stroke, Johns Hopkins University Study
Johns Hopkins neurologists report success with a new means of getting rid of potentially lethal blood clots in the brain safely without cutting through easily damaged brain tissue or removing large pieces of skull.

Servier Mediator Investigation Continues With Home Searches
Investigators searched the offices of French healthcare regulator Afssaps on Thursday in connection with a case involving the anti-diabetes drug Mediator, which officials blame for at least 500 deaths in France. Judicial sources said that investigators also searched the homes of several executives of Afssaps, which is under scrutiny for allowing the sale of Mediator long after it had been pulled from...

Johnson & Johnson Hid Risperdal Studies to Boost Drug Sales, Lawyer Says
Johnson & Johnson hid studies showing its Risperdal anti-psychotic drug caused diabetes to protect billions of dollars in sales, a lawyer said in the first personal-injury claim over the medication to go to trial. Researchers at J&Js Janssen unit knew as early as 1999 that a study found Risperdal caused diabetes at a higher rate than a competing drug and failed to hand over the results to regulators...

Sleep Apnea Ups Risk of Silent Strokes, Study
People with severe sleep apnea may have an increased risk of silent strokes and small lesions in the brain, researchers have revealed. The researchers found that ninety-one per cent (51 of 56) of the patients who had a stroke had sleep apnea and were more likely to have silent strokes and white matter lesions that increased risk of disability at hospital discharge.

Shareholder Group Slams Novartis AG Over Chairman's Pay
Shareholder group Ethos called for Novartis investors to vote against re-electing board members who were among those deciding on the pay awarded to the Swiss drugmaker's chairman, Daniel Vasella. The call is part of an attack on Vasella for "earning a million Swiss francs a month, which goes too far," Ethos director Dominique Biedermann told journalists in Zurich. Vasella's pay rose to 13.5 million...

Rapid Nerve Repair Helps Lame Rats Walk Within Days, University of Texas Study
A simple, cheap procedure for repairing damaged nerves in the leg can help paralysed rats walk normally within a few days a dramatic reduction in recovery time. Within minutes of the rats waking up after the operation, they began to move their damaged limb, and 98 per cent of them had recovered 60 to 70 per cent of leg function within two to four weeks. Conventional treatments would never give the...

Identical Twins Reveal Mechanisms Behind Aging, Uppsala Universitet Study
In a recent study led by Uppsala University, the researchers compared the DNA of identical (monozygotic) twins of different age. They could show that structural modifications of the DNA, where large or small DNA segments change direction, are duplicated or completely lost are more common in older people. The results may in part explain why the immune system is impaired with age.

Federal Court Dismisses Whistleblower Lawsuit Against Millennium Laboratories
SAN DIEGO, Feb. 3, 2012 /PRNewswire/ -- On January 30, 2012, US District Court Judge Joseph L. Tauro ordered the complete dismissal of a whistleblower suit against Millennium Laboratories brought by a former Calloway Laboratories' senior officer. Although the Department of Justice had previously stated...

Erratic Heart Rhythm May Account for Some Unexplained Strokes, Henry Ford Hospital Study
Occasional erratic heart rhythms appear to cause about one-fifth of strokes for which a cause is not readily established, according to research presented at the American Stroke Association's International Stroke Conference 2012.

Merck & Co., Inc. Swings to Profit on Fewer Charges, Sales Growth
Merck & Co. swung to a fourth-quarter profit from a year-earlier loss that was weighed down by an asset write-down for a drug-research setback, while sales inched up 2%. The Whitehouse Station, N.J., drug maker issued a forecast for full-year 2012 results that leaves room for earnings growth, while sales are expected to be flat or down due to the impending loss of U.S. patent protection for its top...

Cardinal Health, Inc. Plans $90 Million in China Acquisitions
February 3, 2012 -- Cardinal Health, the US-based drug distributor, plans to make $90 million in China acquisitions to bolster its geographic coverage in mainland China. In addition, Cardinal said it is expanding its China product offerings to include medical products, lab equipment and other supplies. Cardinal bought a distribution foothold the PRC market in late 2010 by paying $470 million for Zuellig...

AstraZeneca PLC to Axe 7,300 Jobs in Global Restructuring
Drug maker AstraZeneca PLC said it will cut another 7,300 jobs as it warned Thursday of a tough year ahead, due to government spending cuts on healthcare and stiff competition, even as it reported a 24 percent increase in 2011 profits. The Anglo-Swedish company said its full-year profit was $10 billion, up from $8.1 billion a year earlier. The profit advance was helped heavily by a $1.5 billion gain...

Merrimack Pharmaceuticals Inc. Scraps IPO Plans
Boston Business Journal by Julie M. Donnelly, Reporter

Merrimack Pharmaceuticals has postponed its $166 million IPO, originally scheduled for this week, according to IPO tracker Renaissance Capital, due to poor market conditions.

The Cambridge, Mass-based company, which is developing potential treatments for cancer, planned to sell 16,666,667 shares of common stock at an estimated...

National Institute for Clinical Excellence (NICE) Rejects Use of Johnson & Johnson's Prostate Cancer Drug Zytiga
A Johnson & Johnson prostate-cancer medicine discovered in England and developed with funds from U.K. charities is too expensive for the countrys National Health Service. The NHS shouldnt pay for Zytiga because the drugs benefits dont justify the cost even after the manufacturer agreed to cut the price, the National Institute for Health and Clinical Excellence said in a statement today. The agency...

Discovery Laboratories Gets FDA OK for Aerosol Medicines Delivery System
WARRINGTON, Pa., Feb. 2, 2012 /PRNewswire/ -- Discovery Laboratories, Inc. (NASDAQ: DSCO), a specialty biotechnology company dedicated to advancing a new standard in respiratory critical care, today announced AFECTAIR is now registered with the Food and Drug Administration (FDA) and is cleared to be marketed in the United States. AFECTAIR is a proprietary patient...

Genzyme Corporation Hit With Layoffs as Sanofi (France) Integration Continues
Genzyme Corp.s research and development operations in Massachusetts have been cut by an unspecified number of positions, according to parent company Sanofi (NYSE: SNY). The positions have been eliminated to avoid redundancy between Sanofi and Genzyme staff, and do not reflect cuts to any specific drug development programs, the firm said.

Is Eli Lilly and Company???s Alzheimer???s Drug Its Ace in the Hole?
A treatment for Alzheimer's disease is the drug industry's longest shot, and any brave investors willing to place a bet on the outcome are likely to focus on Eli Lilly & Co. Lilly and Pfizer Inc are the farthest along in developing experimental medicines for the memory-robbing disease. But Lilly, as the far smaller company, has much more upside for its share price if it hits pay dirt. The field is...

"Morning-After" Pill May Be New Option to Treat Painful Fibroids, Study
The morning-after pill may help shrink painful fibroids and relieve excessive bleeding, new research indicates. Fibroids are benign tumors that form on the wall of a woman's uterus; as many as 80 percent of all women may have fibroids. Many cause no symptoms, but one in four women experiences symptoms that are severe enough to require treatment, according to the National Uterine Fibroids Foundation...

Cancer Drug Tested at Translational Genomics Research Institute (TGen) Gets FDA Approval
SCOTTSDALE, Ariz., Feb. 1, 2012 /PRNewswire-USNewswire/ -- A new skin cancer drug tested for the first time in the world five years ago at the Virginia G. Piper Cancer Center at Scottsdale Healthcare just received expedited approval by the U.S. Food and Drug Administration, a remarkable accomplishment in new drug development.

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Athersys, Inc. Announces Positive Results of MultiStem(R) Clinical Trial for Hematopoietic Stem Cell Transplant Support and Prevention of Graft-Versus-Host Disease
CLEVELAND, Feb. 1, 2012 (GLOBE NEWSWIRE) -- Athersys, Inc. (Nasdaq:ATHX - News) today announced positive results from its Phase I clinical trial of MultiStem(R), its cell therapy product, administered to individuals undergoing allogeneic hematopoietic stem cell transplants (HSCT) for the treatment of leukemia and related conditions. According to the Center for International Blood and Marrow Transplant...

Drugmakers Including GlaxoSmithKline Scuttle Plan for Approval System Pushed by Biotechs
Drugmakers including GlaxoSmithKline Plc have fought off a U.S. senators proposal that would have approved medicines for diseases that are fatal, or have no existing treatments, based on fewer human trials. The plan, drafted by Democratic Senator Kay Hagan of North Carolina, was being pushed by biotechnology companies to speed up approvals and make the process less expensive. It would have created...

McMaster University Shows How Massage Eases Sore Muscles
Having a massage after strenuous exercise not only feels good, it reduces inflammation in muscles at the cellular level, researchers have found. Massage also appears to promote the growth of new mitochondria in skeletal muscle. Mitochondria are cells' energy-producing "powerhouses," explained the researchers at the Buck Institute for Research on Aging and McMaster University in Hamilton, Ontario....

Ligand Pharmaceuticals Inc. Presents Full Data from Successful Phase II Trial of Captisol-Enabled??, Propylene Glycol-Free Melphalan at the BMT Tandem Meetings
SAN DIEGO--(BUSINESS WIRE)-- Ligand Pharmaceuticals Incorporated (NASDAQ: LGND - News) announced that results from the Phase II study of its Captisol-enabled, propylene glycol-free (PG-free) Melphalan program were featured this evening in a poster presentation at the combined annual meetings of the Center for International Blood & Marrow Transplant Research (CIBMTR) and the American Society for Blood...

Tranzyme Pharma Secures Additional $9.3 Million Debt Financing
RESEARCH TRIANGLE PARK, N.C., Feb. 1, 2012 (GLOBE NEWSWIRE) -- Tranzyme Pharma (Nasdaq:TZYM - News) today announced that it received an additional net $9.3 million in term loan proceeds through an amendment and restatement of its existing debt financing facility with Oxford Finance LLC and Horizon Technology Finance Corporation (Nasdaq:HRZN - News).

"We expect to file the NDA for our intravenous...

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceutical Co. Ltd.'s Bowel Dysfunction Drug Succeeds in Second Phase III Study
BETHESDA, Md. & DEERFIELD, Ill.--(BUSINESS WIRE)--Sucampo Pharmaceuticals, Inc. (NASDAQ: SCMP) (SPI) and Takeda Pharmaceuticals U.S.A., Inc. announced today that lubiprostone met the primary endpoint in a phase 3 clinical trial for the treatment of opioid-induced bowel dysfunction (OBD) in patients with chronic, non-cancer pain, excluding those taking methadone.

Patients received lubiprostone...

The Very Old May Feel Helpless, But Not Depressed, Iowa State University Study
People over 100 years old may say they feel "helpless" and "worthless" because they can't do the things they used to, but that doesn't mean they're not in good spirits suggests a new study.

AHF Calls for Congressional Investigation and Shake Up at FDA
WASHINGTON--(BUSINESS WIRE)-- AIDS Healthcare Foundation (AHF) today called for a top to bottom shake-up of the management at the Food and Drug Administration (FDA) as well as a Congressional investigation following the publication of a Washington Post news article (1/31/12) that reported, ...the Food and Drug Administration secretly monitored the personal e-mail of a group of its own scientists and...

Hybrid Fuels, Inc. Announces FDA Approved Lab Selection for Azul Instant??? - "Be Ready in an Instant"
FORT LAUDERDALE, Fla., Feb. 2, 2012 /PRNewswire/ -- Hybrid Fuels, Inc., (Pink Sheets: HRID) announced today that after a lengthy and heavily scrutinized review process that it has selected a state-of-the-art FDA approved laboratory to manufacture all new orders of Azul Instant.

The laboratory was chosen based on its compliance standards and ability to ramp...

Agennix AG Halts Phase II/III OASIS Trial in Severe Sepsis

PLANEGG, GERMANY and MUNICH, GERMANY--(Marketwire - February 02, 2012) - Agennix AG (FRANKFURT: AGX) (XETRA: AGX) (ISIN DE000A1A6XX4) announced that, upon the recommendation of the study Data Safety Monitoring Board (DSMB), the Company has stopped further enrollment and treatment in the Phase II/III OASIS trial with talactoferrin in severe sepsis. The DSMB made this recommendation...

When Ranked, "Stable" IQ Scores Drop, California Institute of Technology Study
Our cognitive abilities suffer when we feel that we are being ranked, such as in the classroom or at work, new research shows. The finding, from a team of researchers from the California Institute of Technology (Caltech) and four other institutions, flies in the face of long-held ideas about intelligence and cognition that regard IQ as a stable, predictive measure of mental horsepower.

Why the Brain is More Reluctant to Function as We Age, University of Bristol Study
New findings, led by neuroscientists at the University of Bristol and recently published in the journal Neurobiology of Aging, reveal a novel mechanism through which the brain may become more reluctant to function as we grow older.

GlaxoSmithKline Settles 20,000 Lawsuits Over Avandia, Lawyer Says
GlaxoSmithKline Plc (GSK), which is paying $3 billion to resolve government claims that it illegally marketed drugs such as the Avandia diabetes medication, agreed to settle more lawsuits over the pills, a lawyer said. Glaxo, the U.K.s biggest drugmaker, agreed last month to resolve more than 20,000 cases alleging Avandia causes heart attacks, said Paul Kiesel, a lawyer for former users. The accord...

Alzheimer???s Disease Protein Flows Through Brain???s Neurons, Study Suggests
Alzheimer's disease spreads in a predictable pattern like an infection, going from one brain cell to another along linked circuits known as synapses, researchers say. The findings, published in the online journal PloS One, suggest that blocking the process early on may keep the disease from spreading.

Facebook is Not Such a Good Thing for Those With Low Self-Esteem, University of Waterloo Study
In theory, the social networking website Facebook could be great for people with low self-esteem. Sharing is important for improving friendships. But in practice, people with low self-esteem seem to behave counterproductively, bombarding their friends with negative tidbits about their lives and making themselves less likeable, according to a new study which will be published in Psychological Science...

Omega-3 Fatty Acids Tied to Lower Heart Arrhythmia Risk, Harvard School of Public Health Study
Older adults who had the highest blood levels of omega-3 fatty acids, most commonly found in fish, were 30 percent less likely to later develop an irregular heartbeat than peers with the lowest blood levels of omega-3s, according to a U.S. study. Up to nine percent of U.S. residents will develop atrial fibrillation by the time they reach their 80s, according to some estimates. The heart rhythm abnormality...

Medivation, Inc. Soars as Prostate Cancer Drug is Well-tolerated in Phase 3 Trial

SAN FRANCISCO, CA and TOKYO--(Marketwire - January 31, 2012) - Medivation, Inc. (NASDAQ: MDVN) and Astellas Pharma Inc. (TSE: 4503) announced positive results on all efficacy endpoints from the Phase 3 AFFIRM trial of the investigational drug MDV3100 in men with prostate cancer previously treated with chemotherapy...

Pfizer Inc. Recalls 1 Million Birth Control Packs After Mixup
Pfizer Inc. is recalling 1 million packets of birth control pills because of a packaging error that could leave women with an inadequate dose of the hormone-based drugs and raise the risk that they will get pregnant accidentally. The problem affects 14 lots of Lo/Ovral-28 tablets and 14 lots of generic Norgestrel and Ethinyl Estradiol tablets. Both products are manufactured by Pfizer and marketed in...

Men More Likely to Have an Accurate Memory of Unpleasant Experiences, University Of Montreal Study
A woman's memory of an experience is less likely to be accurate than a man's if it was unpleasant and emotionally provocative, according to research undertaken by University of Montreal researchers at Louis-H Lafontaine Hospital.

Are Diet Soft Drinks Bad for You? Study
A new study finds a potential link between daily consumption of diet soft drinks and the risk of vascular events. Individuals who drink diet soft drinks on a daily basis may be at increased risk of suffering vascular events such as stroke, heart attack, and vascular death. This is according to a new study by Hannah Gardener and her colleagues from the University of Miami Miller School of Medicine...

Too Much Testosterone Linked to Inflated Ego, University College London Study
Testosterone makes people more self-centered and less cooperative, a finding that may explain why group decisions can be affected by dominant individuals, researchers report. Their study included 34 females who had never met. The women were divided into 17 pairs and asked to complete a series of tasks designed to assess their levels of cooperation. The tests were conducted on two separate days. On...

Infections Might Raise Stroke Risk in Children, University of California, San Francisco (UCSF) Study
Many children who suffer a stroke had some sort of an infection in the days leading up to the stroke, a new study says. However, childhood stroke is rare and parents shouldn't be unduly alarmed by these findings, the researchers noted.

Valeant Pharmaceuticals International Acquires in Brazil for $85 Million
MISSISSAUGA, Ontario, Feb. 1, 2012 /PRNewswire/ -- Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) announced today that Valeant has acquired Probiotica Laboratorios Ltda., a leader in sports nutrition and food supplements in Brazil. Probiotica currently markets a full line of over-the-counter sports nutrition products and other food supplements, with a 30 percent share...

Dendreon Corporation Taps Savient Pharmaceuticals, Inc.'s as CEO
SEATTLE--(BUSINESS WIRE)--February 1, 2012 Dendreon Corporation (Nasdaq: DNDN) today announced that its Board of Directors has elected John H. Johnson to the position of president and chief executive officer (CEO), to succeed Mitchell H. Gold, MD, who has served as president and CEO for nearly a decade. Dr. Gold has been elected executive chairman and will serve in that role until June 30, 2012...

Sangamo BioSciences, Inc. to Partner With Shire plc for $13 Million to Develop DNA Technology
DUBLIN and RICHMOND, Calif., Feb. 1, 2012 /PRNewswire/ -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, and Sangamo BioSciences, Inc. (NASDAQ: SGMO), a leader in genome-editing technology, announced today that they have entered into a collaboration and license agreement to develop therapeutics for...

Female Frontrunners in Biotech
Excelling in industry is not easy, especially if youre a woman. According to a 2010 study of New England biotech firms, females comprised only about 12 percent of biotech founders, despite earning about half of the biological science PhDs. And women are equally underrepresented at the senior management level, holding just 12 percent of senior executive positions in the worlds top drug companies and...

Merck & Co., Inc. Consolidates Animal Health Offices; Axes 65 Jobs
Merck said today it plans to centralize its animal health business by moving dozens of functions to Summit from operations in the Netherlands. The plan, which must still be reviewed by the Dutch governments Work Council, will involve relocating most of the animal health units commercial, marketing and corporate headquarters operations to the Summit campus. The proposed consolidation follows the company...

"Mind-Reading" Device Comes Closer to Reality as Scientists Decode "Internal Voices," University of California, Berkeley (CAL) Study
Scientists could soon be able to eavesdrop on the constant, internal monologs that run through people's minds, or hear the imagined speech of those patients who cannot speak, a new study has revealed. The scientists at the University of California, Berkeley have succeeded in decoding electrical activity in a region of the human auditory system called the superior temporal gyrus (STG). By analyzing...

McKesson Corporation Buys Canadian Pharmacy Marketing Group Assets for $918 Million
McKesson Corp. (MCK), the biggest U.S. drug distributor, said it agreed to spend about $918 million for the marketing and franchising businesses of more than 1,000 Canadian independent pharmacies. McKesson will buy Drug Trading Co. and Medicine Shoppe Canada Inc. from Katz Group Canada Inc., a closely held Edmonton, Alberta-based company. The deal is expected to close in the first half of this year...

Impax Pharmaceuticals Gains Rights for US Sales of AstraZeneca PLC's Zomig; Paying $130 Million in 2012
HAYWARD, Calif.--(BUSINESS WIRE)-- Impax Pharmaceuticals, the branded products business unit of Impax Laboratories, Inc. (NASDAQ: IPXL - News), announced today that it has licensed from AstraZeneca the exclusive United States (U.S.) commercial rights to Zomig (zolmitriptan) tablet, orally disintegrating tablet, and nasal spray formulations. As part of a Distribution, License, Development and Supply...

Fish Oil in Pregnancy Reduces Infant Eczema, Study
Taking fish oil capsules during pregnancy could help women with a family history of eczema to avoid passing on the condition to their children. A study of 700 pregnant women found that those who took the supplements reduced by one-third the risk their infants would develop eczema, compared with women who took a placebo.

Pfizer Inc., Eli Lilly and Company Profits Fall as Drugs Lose Patents
Drug makers Pfizer Inc. and Eli Lilly & Co. were hurt by the "patent cliff," with each reporting declines in fourth-quarter profit due to new generic competition for top-selling drugs. Both companies also spoke cautiously about experimental Alzheimer's disease drugs they're developing separately, though investor enthusiasm has mounted in the off chance that one or both of the drugs will reach the market...

FDA Approves Boehringer Ingelheim Corporation, Eli Lilly and Company's Diabetics Therapy Jentadueto???
RIDGEFIELD, Conn., and INDIANAPOLIS, Jan. 30, 2012 /PRNewswire/ --Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company (NYSE: LLY) today announced the U.S. Food and Drug Administration (FDA) has approved Jentadueto (linagliptin/metformin hydrochloride) tablets, a new...

Short-Term Memory is Based on Synchronized Brain Oscillations, Max Planck Institute Study
Scientists have now discovered how different brain regions cooperate during short-term memory. Holding information within one's memory for a short while is a seemingly simple and everyday task. We use our short-term memory when remembering a new telephone number if there is nothing to write at hand, or to find the beautiful dress inside the store that we were just admiring in the shopping window. Yet...

FDA Approves Novartis Corporation's Gleevec for Expanded Use in Patients With Rare Gastrointestinal Cancer
SILVER SPRING, Md., Jan. 31, 2012 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration today granted Gleevec (imatinib) regular approval for use in adult patients following surgical removal of CD117-positive gastrointestinal stromal tumors (GIST). Today's action also highlights an increase in overall patient survival when the drug is taken for 36 months...

FDA Approves Vertex Pharmaceuticals Incorporated's Cystic Fibrosis Drug
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) announced today that the U.S. Food and Drug Administration (FDA) has approved KALYDECOTM (ivacaftor), the first medicine to treat the underlying cause of cystic fibrosis (CF), a rare, genetic disease. KALYDECO (kuh-LYE-deh-koh) is approved for people with CF ages 6 and older who have at least one copy of the G55...

Decaffeinated Coffee Preserves Memory Function By Improving Brain Energy Metabolism, Mount Sinai School of Medicine Study
Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type 2 diabetes. This brain dysfunction is a known risk factor for dementia and other neurodegenerative disorders like Alzheimer's disease. The research is published online in Nutritional Neuroscience.

Honey Could Be Effective at Treating and Preventing Wound Infections, Study
Manuka honey could help clear chronic wound infections and even prevent them from developing in the first place, according to a new study published in Microbiology. The findings provide further evidence for the clinical use of manuka honey to treat bacterial infections in the face of growing antibiotic resistance.

AB Science Reports Positive Clinical Study Data: Masitinib Significantly Extends Overall Survival as Compared to Pfizer Inc.'s Sutent??in Gleevec??-resistant GIST
PARIS--(BUSINESS WIRE)--Regulatory News: AB Science SA (Paris:AB) (NYSE Euronext - FR0010557264 - AB) today announced encouraging results from a phase 2 study with its investigational drug, masitinib, in Gleevec-resistant gastrointestinal stromal tumors (GIST). Masitinib significantly improved overall survival in patients with Gleevec-resistant gastrointestinal stromal tumors (GIST) as compared to...

Diabetes Drugs Tied to Pancreatic Cancer Risk, University of California, San Francisco (UCSF) Study
A new study links the diabetes drug metformin to fewer cases of pancreatic cancer -- at least in women -- but finds other diabetes medications are associated with a higher risk of the disease.

Savient Pharmaceuticals, Inc. Appoints Interim Chief Executive Officer
EAST BRUNSWICK, N.J., Feb. 1, 2012 /PRNewswire/ -- Savient Pharmaceuticals, Inc. (Nasdaq: SVNT) today announced that the Company's Board of Directors has appointed David Y. Norton, a member of the Savient Board and former Company Group Chairman, Global Pharmaceuticals for Johnson & Johnson, to the role of Interim Chief Executive...

Eating Fish Tied to Lower Risk of Colon Polyps, Harvard School of Public Health Study
Women who eat about three servings of fish per week have a somewhat lower chance of having polyps found during a routine colonoscopy than women who eat just one serving every two weeks, according to a new study.

Gene Mutation in Autism Found to Cause Hyperconnectivity in Brain's Hearing Center, Cold Spring Harbor Laboratory Study
New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.

Ablynx Receives Another EUR $5 Million Milestone as Boehringer Ingelheim Corporation Selects Nanobody Candidate for Pre-Clinical Development
SOPHIA ANTIPOLIS, France--(BUSINESS WIRE)--MEDIAN Technologies (Paris:ALMDT)(ALMDT), a leading services provider for image interpretation and management in oncology clinical trials, and software provider for medical imaging, announced today the signature of a landmark contract with the top pharmaceutical company SANOFI for the interpretation and end-to-end management of medical images in a phase II...

Could a Club Drug Offer "Almost Immediate" Relief From Depression? Reveals
Ketamine, a prescription drug that has been used as an anesthetic for decades and gained popularity on the street as Special K, is being tested in Houston as a quick fix to severe depression.

FDA Panel Wants Suicide Risk on Novartis AG ADHD Drug Label
Children who take a common drug for attention deficit disorder should be warned about the risk of suicidal thoughts, U.S. pediatric health advisers said on Monday. Several members of an advisory committee to the Food and Drug Administration asked the agency to change the label for Focalin, an attention deficit medicine made by Swiss drugmaker Novartis AG, to reflect this risk. The drug is approved...

Music Training Has Biological Impact on Aging Process, Northwestern University Study
Age-related delays in neural timing are not inevitable and can be avoided or offset with musical training, according to a new study from Northwestern University. The study is the first to provide biological evidence that lifelong musical experience has an impact on the aging process.

Science Shows How Exercise Might Help in Prostate Cancer, University of California, San Francisco (UCSF) Study
Vigorous exercise causes changes in some 180 prostate genes among men with early stage prostate cancer, a new study suggests. Included are genes known to suppress tumor growth and repair DNA, which might mean that exercise could prevent or delay progression of the disease, the researchers said.

New Genetic Subtype of Lung Cancer Defined, Massachusetts General Hospital Cancer Center Study
A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S. The researchers show that ROS1-driven tumors can be treated...

Transparency Life Sciences, LLC Launched as World's First Drug Development Company Based on Open Innovation
New York, NY and Philadelphia, PA - January 31, 2012 - Transparency Life Sciences, LLC (TLS) the worlds first drug development company based on open innovation, announced its official launch today with the introduction of a prototype of the companys crowdsourced web platform that allows patients, physicians, researchers and other stakeholders to contribute to the design of clinical studies. The...

BioSante Pharmaceuticals, Inc. Cuts 25% of Workforce
LINCOLNSHIRE, Ill.--(BUSINESS WIRE)--BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX) today announced a corporate update.

Corporate development: In light of the recently announced top-line results from BioSantes two pivotal Phase III LibiGel (testosterone gel) efficacy trials, BioSante is evaluating its corporate strategy. BioSante continues to investigate alternative strategies to utilize...

Orexo AB, Janssen Pharmaceutical K.K. Axe Preclinical-Stage Deal in Respiratory Diseases
UPPSALA, Sweden--(BUSINESS WIRE)-- Regulatory News: Orexo AB (STO:ORX.ST - News) and Janssen Pharmaceuticals, Inc., formerly Ortho-McNeil-Janssen Pharmaceuticals, Inc. and Janssen Pharmaceutica NV ("Janssen"), have decided to end their research collaboration and license agreement regarding the OX-CLI and OX-ESI programs and a third, undisclosed Janssen program. Each party has regained all commercial...

AstraZeneca AB May Shed Thousands More Jobs
AstraZeneca Plc (AZN), the U.K.s second- biggest drugmaker, is set to announce more job cuts after beginning a cost-cutting program in 2010, the Sunday Times reported today, without citing anyone. Two years ago, chief executive David Brennan said more than 10,000 jobs would be lost by 2014, the newspaper said. The target may be extended significantly when the company announces its annual results on...

AssureRx Secures $8 Million Financing With Silicon Valley Bank to Support Growth
MASON, Ohio, Jan. 31, 2012 /PRNewswire/ -- AssureRx Health, Inc., today announced that it has secured an $8 million Term and Revolving Credit Facility that provides additional capital to support increasing clinical adoption of GeneSightRx and to finance multiple new products...

Bob Temple Changes His Role at FDA, Again
Bob Temple, who is widely viewed as an important overseer of regulatory matters, has been asked to give up his role as the acting director of the FDAs Office of Drug Evaluation 1, so that he can devote more attention to his other position, which is Deputy Center Director for Clinical Science, a job that he assumed in November 2009. As Deputy Center Director for Clinical Science, Bob has played and...

Tech Council of Maryland Appoints as Interim CEO

ROCKVILLE, MD--(Marketwire - January 30, 2012) - The Tech Council of Maryland (TCM), Maryland's largest technology trade association with more than 400 biotechnology and technology members employing more than 200,000 in the region, today announced that Art...

Johnson & Johnson Shakes Up McNeil Consumer Healthcare Unit Again
Johnson & Johnson is shaking up oversight of the troubled unit that makes Tylenol and other over-the-counter medicines once again, naming new leadership less than a year after manufacturing problems sparked a revamp. The New Brunswick, N.J., health-products giant is replacing two company group chairmen who held key roles trying to turn around a consumer business racked by recalls and more than $1 billion...

Alcohol and Your Heart: Friend or Foe? Study
A meta-analysis done by the Centre for Addiction and Mental Health (CAMH) into the relationship between alcohol consumption and heart disease provides new insight into the long-held belief that drinking a glass of red wine a day can help protect against heart disease.

Daiichi Sankyo, Inc. Logs Loss
Daiichi Sankyo Co. said on Tuesday it fell into the red for the fiscal third quarter and further lowered its full-year outlook, hurt again by the stubbornly strong yen and legal costs associated with its Indian unit. The Japanese firm acquired a little more than 60% of Indian generic drugmaker Ranbaxy Laboratories Ltd. for $4.6 billion in 2008. But U.S. government allegations of improper manufacturing...

Skin Transformed Into Brain Cells, Stanford University School of Medicine Study
Skin cells have been converted directly into cells which develop into the main components of the brain, by researchers studying mice in California. The experiment, reported in Proceedings of the National Academy of Sciences, skipped the middle "stem cell" stage in the process.

Genetic Breakthrough for Brain Cancer in Children, Study
An international research team led by the Research Institute of the McGill University Health Centre (RI MUHC) has made a major genetic breakthrough that could change the way pediatric cancers are treated in the future. The researchers identified two genetic mutations responsible for up to 40 per cent of glioblastomas in children -- a fatal cancer of the brain that is unresponsive to chemo and radiotherapy...

"Spam" Meat Tied to Diabetes Risk in Native Americans, Study
Native Americans who often ate processed meat in a can, generically known as "spam" and a common food on reservations, one subsidized by the government -- had a two-fold increased risk of developing diabetes over those who ate little or none, according to a U.S. study.

FDA Approves Genentech's Erivedge (Vismodegib) Capsule, the First Medicine for Adults with Advanced Basal Cell Carcinoma
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that ErivedgeTM (vismodegib) capsule was approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with a type of skin cancer, called basal cell carcinoma (BCC), that has spread to other parts of the body or that has come back after surgery or...

Genetic Regulation of Metabolomic Biomarkers: Paths to Cardiovascular Diseases and Type 2 Diabetes, Study
The research group at the Institute for Molecular Medicine Finland (FIMM) has revealed eleven new genetic regions associated with the blood levels of the metabolites, including new loci affecting well-established risk markers for cardiovascular disease and potential biomarkers for type 2 diabetes.

Grape Seed Extract Kills Head and Neck Cancer Cells, Leaves Healthy Cells Unharmed, University of Colorado Study
Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.

Eli Lilly and Company Profit Slumps on Schizophrenia Drug
Eli Lilly & Co. reported fourth- quarter profit that beat analysts estimates as higher sales of its depression and diabetes medicines helped to counter a 44 percent plunge in revenue from the schizophrenia drug Zyprexa. Net income fell 27 percent to $858.2 million, or 77 cents a share, the Indianapolis-based company said today in a statement. Profit excluding certain items beat by 6 cents the average...

Teva Pharmaceutical Industries Limited's Cephalon, Inc. Recalls Treanda Leukemia Drug Due to Glass Fragments
Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA; TASE: TEVA) US subsidiary Cephalon has recalled a lot of its Treanda leukemia drug, because glass fragments were found in one of the vials. The US Food and Drug Administration (FDA) said in a statement that Cephalon distributed the Treanda lot TB30111 to wholesalers and distributors between March 22 and October 5, 2011, and notified those recipients...

Testicular Zap "May Stop Sperm," University of North Carolina Study
A dose of ultrasound to the testicles can stop the production of sperm, according to researchers investigating a new form of contraception.

GlaxoSmithKline, Eli Lilly and Company, Pfizer Inc. Said to be Interested in Turkey's
GlaxoSmithKline Plc (GSK), Eli Lilly & Co. and Pfizer Inc. (PFE) are among about half a dozen companies interested in buying a stake in Mustafa Nevzat Ilac Sanayii AS in a deal that may value the Turkish drugmaker at $1 billion, three people with knowledge of the situation said. The owners of Mustafa Nevzat, or MN Pharmaceuticals as the Istanbul-based company is known, have hired Bank of America Merrill...

Pfizer Inc. to Seek OK for Long-Stalled Menopause Drug
Pfizer Inc. is preparing to seek U.S. regulatory approval to sell a new menopause drug that could pose an alternative to the company's older hormone-replacement therapies, which have been tied to safety risks. However, repeated delays in developing the new drug, Aprela, have raised questions about its potential. Some analysts and doctors question whether regulators will approve it, and Aprela's market...

FDA Approves Amylin Pharmaceuticals, Inc. and Alkermes plc's BYDUREON??? -- The First and Only Once-Weekly Treatment for Type 2 Diabetes
SAN DIEGO and DUBLIN, Jan. 27, 2012 /PRNewswire/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Alkermes plc (Nasdaq: ALKS) today announced that the U.S. Food and Drug Administration (FDA) has approved BYDUREON (exenatide extended-release for injectable suspension) the first once-weekly treatment for type 2 diabetes. BYDUREON...

Teva Pharmaceutical Industries Limited Eyes $2 Billion Micro Laboratories, Inc. Acquisition
The fact that Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA; TASE: TEVA) has explicitly said that it has no plans to make large acquisitions any time soon has not stopped speculations about the company's next buyout. Indian website "VCCircle" reports that Teva is a contender to acquire Micro Labs Ltd. for almost $2 billion. While the amount is not on the scale of Teva's last three multibillion...

FDA Approves Pfizer Inc.'s INLYTA?? (axitinib) for Patients With Previously Treated Advanced Renal Cell Carcinoma (RCC)
NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved INLYTA (axitinib), a kinase inhibitor, for the treatment of patients with advanced renal cell carcinoma (RCC) after failure of one prior systemic therapy. The approval is based on data from the Phase 3 AXIS trial, which demonstrated that INLYTA significantly extended progression free...

160 Novartis AG Temporary Employees Without Jobs
Novartis in Lincoln reduced it's temporary employee workforce by 160 people. Novartis released the information through a statement Saturday. It did not say when the employees were notified and Novartis did not explain why the workers were released. However, the plant in Lincoln shut down in the end of December after a problem caused powerful prescription pain pills to get mixed up with over-the-counter...

FDA Gets Sued for Snooping on Workers
UNITED STATES GOVERNMENT AGENCY, the Food and Drug Administration is being sued by staffers who say that it has secretly monitored their personal email and snooped on their whisteblower warnings. A report at the Washington Post says that the FDA turned its eyes inward after some scientists and doctors warned the US Congress that it was approving medical devices that could harm patients.

Drugmakers Including GlaxoSmithKline and Sanofi (France) Join $785 Million Tropical-Disease Fight
LONDON, Jan. 30, 2012 /PRNewswire-USNewswire/ -- Today, 13 pharmaceutical companies, the U.S., U.K. and U.A.E governments, the Bill & Melinda Gates Foundation, the World Bank and other global health organisations announced a new, coordinated push to accelerate progress toward eliminating or controlling 10 neglected tropical diseases (NTDs) by the end of the decade.

Uniting efforts with NTD...

Bayer AG Gets Approval for Gadovist For Children Aged 2-6 Years
German pharmaceutical company Bayer AG (BAYN.XE) said Friday it got approval for use of Gadovist 1.0 in children aged two to six years in the Europe Union. Gadovist is a contrast medium, which is injected to make diseases visible in magnetic resonance tomography examinations, an imaging technique. It is approved for the most frequently conducted contrast enhanced magnetic resonance tomography examinations...

Amsterdam Molecular Therapeutics (AMT) Announces European Commission (EC) Delays Decision on Glybera?? Marketing Authorisation and Requests Further Information From the
AMSTERDAM, January 30, 2012 /PRNewswire/ --

Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, was informed on Friday January 27, 2012 after business hours that the European Commission's Standing Committee of the European Parliament discussed on Monday January...

GlaxoSmithKline Seeking Acquisition in Turkey
GlaxoSmithKline Plc (GSK), the U.K.s largest drugmaker, is seeking an acquisition in Turkey as it struggles to become profitable in the country, Hurriyet said, citing the companys emerging markets president. Potential targets include producers of cardiovascular drugs or businesses with production facilities that would add value to Glaxos operations, Hurriyet cited Abbas Hussain as saying. Glaxo...

Valeant Pharmaceuticals International Withdraws Bid for ISTA Pharmaceuticals, Inc.
MISSISSAUGA, Ontario, Jan. 30, 2012 /PRNewswire/ -- Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) today announced that it has withdrawn its offer to acquire ISTA Pharmaceuticals Inc. (Nasdaq: ISTA) for $7.50 per share in cash. Valeant had previously announced that the offer would only remain open until

KineMed, Inc. Announces Research Collaboration with Pfizer Inc. for the Advancement of Novel Approaches in Metabolic Disease
EMERYVILLE, Calif.--(BUSINESS WIRE)-- KineMed, Inc. (www.kinemed.com) today announced a non-exclusive research collaboration with Pfizer Inc. (NYSE:PFE - News) for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes. The collaboration will employ KineMeds Dynamic ProteomicsTM technology platform to map the impact of potential drug candidates on specific metabolic...

Social Skills Suffer When Tweens Multitask, Stanford University Study
Tween girls who spend endless hours multitasking on digital devices tend to be less successful with social and emotional development, say researchers.

Lannett Company, Inc. Receives FDA Approval for Hydrochlorothiazide Capsules, 12.5 mg
PHILADELPHIA--(BUSINESS WIRE)-- Lannett Company, Inc. (NYSE AMEX: LCI) today announced it has received approval from the U.S. Food and Drug Administration (FDA) of its Abbreviated New Drug Application (ANDA) for Hydrochlorothiazide Capsules, 12.5 mg. Hydrochlorothiazide Capsules, 12.5 mg, is therapeutically equivalent to the reference listed drug, MicrozideCapsules, 12.5 mg, of Watson Pharmaceuticals...

Antitrust: Commission Closes Procedural Case Against Servier
(NewDesignWorld Press Center) - Brussels - The Commission has closed an investigation into Les Laboratoires Servier for suspected provision of misleading and incorrect information to the Commission's pharmaceuticals sector inquiry.

In 2010, the Commission addressed statements of objections to Les Laboratoires Servier and Servier SAS, a French pharmaceutical company, taking the provisional...

BTG plc's Varicose-vein Drug Succeeds in US Study
Given the medical tech specialist also produces an antidote for snake venom, Varisolve may not be BTG's most glamorous product. Yet the news that its varicose-vein treatment has passed a major trial with flying colours not only saw the group shoot up to an eight-year high today but also put its takeover potential back in the spotlight. The path to production for Varisolve - which treats the affliction...

Infinity Pharmaceuticals Inc. Halts Phase II Cancer Drug Trial
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) today announced interim data from its double-blind, randomized, placebo-controlled Phase 2 study comparing saridegib (also known as IPI-926) in combination with gemcitabine to placebo plus gemcitabine in 122 patients with previously untreated, metastatic pancreatic cancer. The primary endpoint of the Phase 2 study is overall...

Blood Pressure Differences Between Arms Could Signal Heart Risk, University of Exeter Study
People whose systolic blood pressure -- the upper number in their reading -- is different in their left and right arms may be suffering from a vascular disease that could increase their risk of death, British researchers report.

Body Clock Receptor Linked to Diabetes in New Genetic Study, Imperial College London Reveals
A study recently published in Nature Genetics has found new evidence for a link between the body clock hormone melatonin and type 2 diabetes. The study found that people who carry rare genetic mutations in the receptor for melatonin have a much higher risk of type 2 diabetes.

Brain-Derived Neurotrophic Factor: Finding May Have Implications for Rett Syndrome, Other Neurological Disorders, Oregon Health & Science University (OHSU) Study
Researchers at Oregon Health & Science University have discovered that a molecule critical to the development and plasticity of nerve cells -- brain-derived neurotrophic factor (BDNF) -- is severely lacking in brainstem neurons in mutations leading to Rett syndrome, a neurological developmental disorder. The finding has implications for the treatment of neurological disorders, including Rett syndrome...

For Diabetics Not on Insulin, Self-Monitoring Blood Sugar Has No Benefit, VU University Medical Center Study
For type 2 diabetics who are not on insulin, monitoring their blood sugar does little to control blood sugar levels over time and may not be worth the effort or expense, according to a new evidence review.

A Glass of Milk a Day Could Benefit Your Brain, Study
Pouring at least one glass of milk each day could not only boost your intake of much-needed key nutrients, but it could also positively impact your brain and mental performance, according to a recent study in the International Dairy Journal.1 Researchers found that adults with higher intakes of milk and milk products scored significantly higher on memory and other brain function tests than those who...

Acupuncture May Boost Pregnancy Success Rates, Reveals
When a couple is trying to have a baby and can't, it can be emotionally and financially draining. But help may be available in an unexpected form: acupuncture. Medical experts believe that this ancient therapy from China, which involves placing numerous thin needles at certain points in the body, can help improve fertility in both men and women.

Swimming Lowers Older Adults' Blood Pressure, University of Texas Study
Many older adults like to take a dip a pool, and now a small study suggests it can be good for their blood pressure. Researchers found that among 43 older men and women, those who started swimming a few times a week lowered their systolic blood pressure -- the "top" number in a blood pressure reading.

Caffeine May Alter Women's Estrogen Levels, Study
Caffeine changes women's estrogen levels and has different effects in Asian and white women, a new study says. More than 250 women, ages 18 to 44, took part in the study between 2005 and 2007. On average, they consumed 90 milligrams of caffeine a day, about the equivalent of one cup of caffeinated coffee.

The Hotbed Driving Force in Biotech: Massachusetts
By Michelle Wong, BioSpace.com

Massachusetts is picking up steam in the biotech industry while...

Pfizer Inc. Sued by Employees Over Retirement Plans
Employees of Pfizer Inc. have filed suit against the company, alleging the world's largest drug maker failed to properly manage its retirement plans and caused losses totaling hundreds of millions over the past decade in one of the hubs of the pharmaceutical industry. The suit, filed Wednesday in federal court in Puerto Rico, alleges Pfizer allowed employees to amass such high concentrations of company...

Verastem, Inc. Bucks the Trend, Raises $55 Million in IPO
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Verastem, Inc., a biopharmaceutical company focused on discovering and developing drugs to treat breast and other cancers by targeting cancer stem cells, today announced the pricing of its initial public offering of 5,500,000 shares of its common stock at $10.00 per share, before underwriting discounts and commissions. All of the shares in the offering are being sold...

BioSpace.com Featured News and Stories

 

Can Human Genome Really Double Its Stock Price? (HGSI)
At the end of December, we usually review the biotech sector to see which stocks have the most upside for the year ahead.  The basis of the “implied upside” is the consensus mean estimate from Thomson Reuters.  Sometimes the pack of analysts is very right, and sometimes they all get blind-sided.  It was interesting to [...]

Alimera Implosion Analysis, What Is Next (ALIM, PSDV)
Alimera Sciences, Inc. (NASDAQ: ALIM) is the latest of the drug implosions and this one looks even worse than just severely damaging.  The FDA’s complete response letter is really a request for additional data.  This is almost as bad as it could be, short of an outright rejection with an order of termination, for its diabetic [...]

Implosion Analysis For Targacept… What Lies Ahead? (TRGT, AZN)
Tuesday has been an awful day for shareholders of Targacept Inc. (NASDAQ: TRGT).  The company shares lost more than half of their value on news that initial test results from the Phase III antidepressant (TC-5214) failed to meet their endpoints in treating major depressive disorder.  Targacept is covered under a co-development pact with AstraZeneca PLC [...]

Rare Analyst Calls With Huge Upside in Vical and VIVUS (VICL, VVUS, BMY)
Vical Inc. (NASDAQ: VICL) and VIVUS, Inc. (NASDAQ: VVUS) are both running higher this Friday on news that Credit Suisse initiated both biotech outfits with “Outperform” ratings.  What matters more than the call are the price targets and the inferences made in the research calls. Vical Inc. (NASDAQ: VICL) is rarely given huge analyst calls [...]

Top Biotechs With Upside Ahead of Earnings (GILD, AMLN, ARIA, INCY, JAZZ, DNDN, HGSI, ILMN, AMGN, CELG, BIIB, BMRN, LIFE, REGN, AMLN, CBST, ONXX, THRX, VPHM)
Earnings season is afoot and we wanted to see how the analysts are ranking the top biotech stocks before these companies begin their earnings reports.  We pulled the top biotech and biohealth related stocks which have market caps of $1 billion and higher and we broke these out into three separate groups by size.  The [...]

Odds-Making on a Human Genome Sciences Acquisition (HGSI, GSK, BIIB, MRK)
Human Genome Sciences Inc. (NASDAQ: HGSI) is surging on reports that GlaxoSmithKline PLC (NYSE: GSK) could be set to make a $25.00 per share offer to acquire the company.  The report surfaced in the Daily Mail out of the United Kingdom, and we would note that this publication pushes out enough rumors that it could [...]

Unusual Analyst Upgrade & Endorsement for Cell Therapeutics (CTIC)
Cell Therapeutics, Inc. (NASDAQ: CTIC) is a controversial stock in the field of cancer and the company is still aiming for a 2012 debut market launch for its pixantrone drug candidate.  In the last couple of weeks it had reported more positive data and the FDA had earlier this year noted that pixantrone would need [...]

Private Equity Changes CRO Landscape With PPD Buyout (PPDI, CRL, CVD, PRXL)
The world of contract research organizations is changing.  The unexpected news hit the wire this Monday that Pharmaceutical Product Development, Inc. (NASDAQ: PPDI) is being acquired.  This was no gobble-up acquisition where a larger public company preyed on a smaller company.  This was a private equity transaction. PPD has entered into a definitive merger agreement [...]

More Signs of Life for Obesity Drugs (VVUS, OREX, ARNA)
VIVUS Inc. (NASDAQ: VVUS) is getting yet one more sign of life for its Qnexa drug aimed at treating obesity.  The emerging drug outfit has reached an agreement with the FDA on resubmitting its new drug application as an obesity treatment. Here is the plan: “VIVUS intends to resubmit the QNEXA NDA by the end [...]

Beyond the Dendreon Implosion… What To Look For Next (DNDN)
This morning we gave a full preliminary analysis of the implosion happening at Dendreon Corporation (NASDAQ: DNDN) at 24/7 Wall St.  What is obvious as a heart attack, or as obvious as metastatic prostate cancer, is that the market is bracing for far worse news than what has been seen so far.  The price drop [...]

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